Model Organisms in Drug Discovery || Growing Yeast for Fun and Profit: Use ofSaccharomyces Cerevisiae as a Model System in Drug Discovery

✍ Scribed by Carroll, Pamela M.; Fitzgerald, Kevin

• Publisher: John Wiley & Sons, Ltd
• Year: 2003
• Tongue: English
• Weight: 426 KB
• Category: Article
• ISBN-13: 9780470014066
• DOI: 10.1002/0470014067.ch2

✦ Synopsis

Yeast has great utility as a surrogate system to study aspects of mammalian biology. This utility extends to the drug discovery process, where yeast has been used to reveal the mechanism of action of compounds, to discover and characterize components of signaling pathways and to dissect protein function. These applications of yeast are illustrated by examples of research published by major pharmaceutical companies.