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Model for Counterion-Membrane-Fixed Ion Pairing and Donnan Equilibrium in Charged Membranes

✍ Scribed by Mafé, S.; Ramírez, P.; Tanioka, A.; Pellicer, J.

Book ID
121475195
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
236 KB
Volume
101
Category
Article
ISSN
0022-3654

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Donnan Equilibrium of Ionic Drugs in pH-
Donnan Equilibrium of Ionic Drugs in pH-Dependent Fixed Charge Membranes: Theoretical Modeling
✍ Patricio Ramı́rez; Antonio Alcaraz; Salvador Mafé; Julio Pellicer 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 194 KB

We have studied theoretically the partition equilibrium of a cationic drug between an electrolyte solution and a membrane with pH-dependent fixed charges using an extended Donnan formalism. The aqueous solution within the fixed charge membrane is assumed to be in equilibrium with an external aqueous