𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Model for complex physiological processes

✍ Scribed by Yu. N. Onopchuk


Book ID
105059966
Publisher
Springer US
Year
1980
Tongue
English
Weight
692 KB
Volume
15
Category
Article
ISSN
1573-8337

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Utility of a physiologically–based pharm
✍ Joseph A. Grillo; Ping Zhao; Julie Bullock; Brian P. Booth; Min Lu; Kathy Robie- πŸ“‚ Article πŸ“… 2012 πŸ› John Wiley and Sons 🌐 English βš– 535 KB

Background: Rivaroxaban is an oral Factor Xa inhibitor. The primary objective of this communication was to quantitatively predict changes in rivaroxaban exposure when individuals with varying degrees of renal impairment are co-administered with another drug that is both a P-gp and a moderate CYP3A4