✦ LIBER ✦
Model for 82Sr/82Rb generator elution profiles: A secondary approach to radioassay/dosimetry
✍ Scribed by Vijay Dhawan
- Publisher
- Elsevier Science
- Year
- 1987
- Weight
- 567 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0883-2889
No coin nor oath required. For personal study only.
✦ Synopsis
Static (dose calibrator) assays of 82Rb bolus yield erroneous estimates of administered activity by ignoring the asymmetric output of 82Sr/82Rb generators. Though on-line monitoring of elution profile improves accuracy for quantitative purposes, it requires an elaborately shielded detector and associated electronics at patient-study site. Our alternative approach based on mathematical description of the dynamic characteristics of the generator accurately predicts elution profiles over a broad range of flow rates.