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Mode of invasion and lymph node metastasis in squamous cell carcinoma of the oral cavity

✍ Scribed by Yamamoto, Etsuhide ;Miyakawa, Akira ;Kohama, Gen-Iku

Publisher: Wiley (John Wiley & Sons)
Year: 1984
Weight: 821 KB
Volume: 6
Category: Article
ISSN: 0148-6403
DOI: 10.1002/hed.2890060508

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✦ Synopsis

Abstract

The relationship between the mode of tumor invasion in the tumor‐host borderline and the frequency of regional lymph node metastasis was investigated in squamous cell carcinoma of the oral cavity. Cases with grades 1‐3 mode of invasion classified by modified Jacobsson criteria showed a low frequency of metastasis (10/72, 13.9%), while those cases with grade 4 mode of invasion, which consisted of grade 4C (cord‐like type) and grade 4D (diffuse type) showed a high frequency of metastasis (4C:11/18,61.1%;4D:9/12,75.0%; total 20/30,66.7%). Moreover, the number of metastatic nodes in each case of mode of invasion ranged from 1 to 3 in grades 1‐3, from 1 to 5 in grade 4C, and from 1 to 7 in grade 4D. The presence of metastasis indicated a poorer prognosis than did the absence of the mode of invasion in each grade, especially in grades 4C and 4D.

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