Linkage analysis assuming a single-locus
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David A. Greenberg; D. C. Rao
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Article
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1990
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John Wiley and Sons
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English
β 772 KB
## Abstract What happens to the results of linkage analysis when one assumes that a disease results from a single genetic locus with reduced penetrance when the actual cause is two epistatically interacting loci? We wanted to (1) determine whether assuming the correct mode of inheritance at the lin