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Mode of degradation of myofibrillar proteins by an endogenous protease, cathepsin L

✍ Scribed by Ushio Matsukura; Akihiro Okitani; Tetsuo Nishimuro; Hiromichi Kato


Book ID
113124360
Publisher
Elsevier Science
Year
1981
Weight
691 KB
Volume
662
Category
Article
ISSN
0005-2744

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## Abstract A host‐cell‐related proteolytic activity was identified in a recombinant Fc‐fusion protein production process. This report describes the strategy applied to characterize and isolate the enzyme responsible for this degradation by combining cell culture investigation and dedicated analyti