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Mode of blockade by MK-801 of N-methyl-d-aspartate-induced increase in intracellular Ca2+ in cultured mouse hippocampal neurons

✍ Scribed by Michisuke Yuzaki; Atsushi Miyawaki; Kyoko Akita; Yoshihisa Kudo; Akihiko Ogura; Hidetoshi Ino; Katsuhiko Mikoshiba


Book ID
115800844
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
578 KB
Volume
517
Category
Article
ISSN
0006-8993

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## Abstract Cortical primary cultures were loaded with the fluorescent indicator fluo‐3 for assessment of intracellular‐free Ca^2+^ ions with the aid of a confocal laser‐scanning microscope. The addition of __N__‐methyl‐D‐aspartic acid (NMDA) markedly increased the number of fluorescent cells in a