Mode of action considerations in the use of transgenic animals for mutagenicity and carcinogenicity evaluations
β Scribed by B Bhaskar Gollapudi; William T Stott; Barry L Yano; James S Bus
- Book ID
- 119539696
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 241 KB
- Volume
- 102-103
- Category
- Article
- ISSN
- 0378-4274
No coin nor oath required. For personal study only.
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## Abstract In response to the 2005 revised US Environmental Protection Agency (EPA) Cancer Guidelines, a Risk Assessment Forum's Technical Panel has devised a strategy in which genetic toxicology data combined with other information are assessed to determine whether a carcinogen operates through a
## Abstract In response to the 2005 revised U.S Environmental Protection Agency's (EPA) Cancer Guidelines, a strategy is being developed to include all mutagenicity and other genotoxicity data with additional information to determine whether the initiating step in carcinogenesis is through a mutage