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MOC-31 aids in the differentiation between adenocarcinoma and reactive mesothelial cells

✍ Scribed by Morgan, Richard L. ;De Young, Barry R. ;McGaughy, Violeta R. ;Niemann, Theodore H.

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 310 KB
Volume: 87
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19991225)87:6<390::aid-cncr10>3.0.co;2-4

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✦ Synopsis

BACKGROUND.

Evaluation of effusion specimens for the presence of adenocarcinoma often is complicated by the presence of reactive mesothelial cells that can mimic adenocarcinoma. Ancillary studies, in particular immunohistochemistry, can be helpful in making this distinction. MOC-31 is an antibody that recently was reported to be useful in distinguishing adenocarcinoma from mesothelioma in tissue specimens. In this study we examined the utility of this antibody in pleural effusions.

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