Targeted transduction of CD34+ hematopoi
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Min Liang; Nonia Pariente; Kouki Morizono; Irvin S. Y. Chen
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Article
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2009
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John Wiley and Sons
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English
⚖ 973 KB
## Abstract ## Background Conventional gene‐therapy applications of hematopoietic stem cells (HSCs) involve purification of CD34+ progenitor cells from the mobilized peripheral blood, __ex vivo__ transduction of the gene of interest into them, and reinfusion of the transduced CD34+ progenitor cell