Mobile elements and the human genome

✍ Scribed by Luning Prak, Eline T.; Kazazian, Haig H.

• Book ID: 109771306
• Publisher: Nature Publishing Group
• Year: 2000
• Tongue: English
• Weight: 515 KB
• Volume: 1
• Category: Article
• ISSN: 1471-0056
• DOI: 10.1038/35038572

✦ Synopsis

Genomic DNA is often thought of as the stable template of heredity, largely dormant and unchanging, apart from perhaps the occasional point mutation. But it has become increasingly clear that DNA is dynamic rather than static, being subjected to rearrangements, insertions and deletions. Much of this plasticity can be attributed to transposable elements and their genomic relatives.