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Mo1538 Hepatitis B Virus Surface Antigen Suppresses Innate and Adaptive Immune Responses of Murine and Human Liver Cells

✍ Scribed by Jiang, Min; Trippler, Martin; Bröring, Ruth; Poggenpohl, Lena; Gerken, Guido; Lu, Mengji; Schlaak, Joerg F.

Book ID
121922852
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
56 KB
Volume
142
Category
Article
ISSN
0016-5085

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Hepatitis B virus suppresses toll-like receptor–mediated innate immune responses in murine parenchymal and nonparenchymal liver cells
✍ Jun Wu; Zhongji Meng; Min Jiang; Rongjuan Pei; Martin Trippler; Ruth Broering; A 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 839 KB

We have previously shown that Toll-like receptor (TLR)-activated murine nonparenchymal liver cells [(NPC); Kupffer cells (KC), liver sinusoidal endothelial cells (LSEC)] can suppress hepatitis B virus (HBV) replication. Therefore, the aim of this study was to investigate whether HBV has the ability