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Mo1008 Role of TWEAK in the Pathogenesis of Nonalcoholic Fatty Liver Disease

✍ Scribed by Polat, Zulfikar; Uygun, Ahmet; Ozel, A. Melih; Basaranoglu, Metin; Aslan, Fatih; Gulsen, Mustafa; Bagci, Sait

Book ID
122191033
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
290 KB
Volume
144
Category
Article
ISSN
0016-5085

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The pathogenesis of nonalcoholic steatohepatitis (NASH) is poorly defined. Feeding mice a diet deficient in methionine and choline (MCD diet) induces experimental NASH. Osteopontin (OPN) is a Th1 cytokine that plays an important role in several fibroinflammatory diseases. We examined the role of OPN