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Mo-P6:405 Familial defective apolipoprotein B-100 in Poland - high prevalence of APOB ARG3500GLN mutation

✍ Scribed by Bednarska-Makaruk, M.; Broda, G.; Rywik, S.; Wehr, H.


Book ID
118634311
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
146 KB
Volume
7
Category
Article
ISSN
1567-5688

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Familial ligand-defective apolipoprotein
✍ JP RabΓ¨s; M Varret; B Saint-Jore; D Erlich; G Jondeau; M Krempf; P Giraudet; C J πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 161 KB

## Communicated by Michel Goossens Familial ligand-defective apolipoprotein B-100 (FDB) is an autosomal dominant disorder leading to plasma LDL cholesterol elevation and coronary artery disease (CAD). Two specific mutations in the APOB gene-R3500Q and R3531C-induce FDB. We report an original metho