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Mn(OAc)3·2H2O-mediated three-component, one-pot, condensation reaction: an efficient synthesis of 4-aryl-substituted 3,4-dihydropyrimidin-2-ones

✍ Scribed by K Ananda Kumar; M Kasthuraiah; C Suresh Reddy; C Devendranath Reddy


Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
114 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis


4-Aryl-substituted 3,4-dihydropyrimidin-2-ones are synthesized in high yields by one-pot cyclocondensation reactions of aldehydes, b-ketoesters and urea using a catalytic amount of manganese acetate in refluxing acetonitrile.


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Three Component Reaction: An Efficient S
✍ Vinod Tribhuvannathji Kamble; Dnyanoba Baburao Muley; Sandeep Tukaram Atkore; Sh 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 60 KB 👁 1 views

## Abstract Fluoroboric acid supported on silica gel (HBF~4~‐SiO~2~) catalyzes efficiently the three component condensation of an aldehyde, a 1,3‐dicarbonyl compound and urea or thiourea to afford the corresponding 3,4‐dihydropyrimidin‐ 2(1__H__)‐ones and thiones in high yields. The ambient conditi