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MMP1 and MMP20 contribute to tooth agenesis in humans

✍ Scribed by Erika C. Küchler; Renato Menezes; Nicholas Callahan; Marcelo C. Costa; Adriana Modesto; Raquel Meira; Asli Patir; Figen Seymen; Katiúcia B.S. Paiva; Fabio Daumas Nunes; José Mauro Granjeiro; Alexandre R. Vieira


Book ID
113466404
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
158 KB
Volume
56
Category
Article
ISSN
0003-9969

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## Membrane -type 1 matrix metalloproteinase (MT1-MMP) is a presumed activator of MMP2, which is one of the major proteinases in tumor cell invasion. In this study, we determined the clinico-pathologic significance of MT1-MMP expression in 68 human gastric carcinomas. The tumor-normal ratio (T/N r