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MMP AND VEGF REGULATION IN ENDOTHELIAL CELL-SEEDED UBM EXTRACELLULAR MATRIX IN A BIOREACTOR

✍ Scribed by Anthony Callanan; Liam Morris; Stephen F. Badylak; Tim McGloughlin


Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
121 KB
Volume
41
Category
Article
ISSN
0021-9290

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## Abstract Basic fibroblast growth factor (FGF‐2) and matrix metalloproteinases (MMPs) play key roles in vascular remodeling. Because FGF‐2 controls a number of proteolytic activities in various cell types, we tested its effect on vascular endothelial cell expression of MMP‐3 (stromelysin‐1), a br