MMP-1 polymorphisms and the risk of idiopathic pulmonary fibrosis
✍ Scribed by Marco Checa; Víctor Ruiz; Martha Montaño; Rafael Velázquez-Cruz; Moisés Selman; Annie Pardo
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 403 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0340-6717
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📜 SIMILAR VOLUMES
The fibrotic process of idiopathic pulmonary fibrosis (IPF) is considered to be the consequence of an exaggerated response to an inflammatory lung injury. In a previous report, except for the response to PG-E 2 , we found no difference in the proliferative profiles of lung fibroblasts between IPF pa
## Communicated by Stephen Chanock Matrix metalloproteinases (MMPs) play important roles in cancer initiation and development. Several polymorphisms in the promoters of a number of MMP genes, which can affect the respective MMP production in an allele-specific manner, have been well characterized.
## Abstract ## Objectives/Hypothesis: Matrix metalloproteinase‐1 (MMP‐1) is associated with a risk of inflammatory disease and cancer invasion. Two common etiologies for sudden deafness (SD) are circulatory disturbance and inflammation. The present study aimed to investigate whether MMP‐1 polymorp