๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

MK-677, an Orally Active Growth Hormone Secretagogue, Reverses Diet-Induced Catabolism

โœ Scribed by Murphy, M. G.


Book ID
118026283
Publisher
Endocrine Society
Year
1998
Tongue
English
Weight
152 KB
Volume
83
Category
Article
ISSN
0021-972X

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Synthesis of the orally active spiroindo
โœ Peter E. Maligres; Ioannis Houpis; Kai Rossen; Audrey Molina; Jess Sager; Veena ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 706 KB

The preparation of the Merck Growth Hormone Secretagogue; MK-677 is described. A Fischer indole/reduction based strategy provides the novel spiroindoline nucleus of this potent compound. This optimized sequence necessitates the isolation of only one intermediate 10 and provides MK-677 in 48% overall