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MK-462 in migraine: A pilot study.

✍ Scribed by Cutler, N.R.; Claghorn, J.; Sramek, J.J.; Block, G.; Panebianco, D.; Cheng, H.; Olah, T.V.; Reines, S.A.


Book ID
110019715
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
151 KB
Volume
59
Category
Article
ISSN
0009-9236

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A study was conducted to assess the safety, tolerability, and pharmacokinetics of single intravenous (IV) doses of 5-90pgkg-' of MK-462, and the effect of food on the pharmacokinetics of MK-462 administered orally to healthy males. Results of this study indicate that IV doses of MK-462 from 5 to 90p