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Mixture of fibroblast, epithelial and endothelial cells conditioned media induce monocyte-derived dendritic cell maturation

✍ Scribed by Meysam GanjiBakhsh; Vahid Nejati; Nowruz Delirezh; Masoumeh Asadi; Keykavos Gholami


Book ID
113527495
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
848 KB
Volume
272
Category
Article
ISSN
0008-8749

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## Abstract ## Background The development of dendritic cell (DC)‐based vaccines using antigen‐encoding mRNA requires identification of the critical parameters for efficient __ex vivo__ loading of DCs. Exogenously delivered mRNA can induce DC activation, but the molecular mechanisms involved are un