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Mixture effects of dietary flavonoids on steroid hormone synthesis in the human adrenocortical H295R cell line

✍ Scribed by Åsa Ohlsson; Erik Ullerås; Nina Cedergreen; Agneta Oskarsson

Book ID: 116463540
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 384 KB
Volume: 48
Category: Article
ISSN: 0278-6915
DOI: 10.1016/j.fct.2010.08.021

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## Abstract The present study was to investigate the effects and action mechanisms of digoxin and ouabain on steroidogenesis in human adrenocortical NCI‐H295 cells. Administration of digoxin or ouabain for 24 h decreased the basal and angiotensin II (Ang II)‐stimulated release of aldosterone by NCI