Dose-dependent induction and suppression
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Akio Koizumi; Miho Kumai; Masayuki Ikeda
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Article
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1983
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John Wiley and Sons
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English
โ 950 KB
The effect of continuous exposure to trichloroethylene (TRI), tetrachloroethylene (TETRA) or methylchloroform (MC) on the hepatic mixed-function oxidase system (MFOS) was studied in rats by using 10 000 x g supernatant fraction. Exposure to TETRA for 240 h at 200, 100 and 50 ppm enhanced oxidative c