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Mitoxantrone, etoposide, mitoguazone and vinblastine chemotherapy (MV2) in relapsed and refractory lymphomas

✍ Scribed by John P. Crown; Subhash Gulati; David J. Straus; Jonathan Kolitz; Robert Heelan; James O'Brien; Burton J. Lee; Carol Portlock; Joseph Bertino

Book ID: 104652088
Publisher: Springer US
Year: 1991
Tongue: English
Weight: 142 KB
Volume: 9
Category: Article
ISSN: 0167-6997
DOI: 10.1007/bf00175086

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✦ Synopsis

As part of a program to develop less leukemogenic chemotherapy regimens for the treatment of favorable prognosis Hodgkin's disease, a phase I-II trial of mitoxantrone, etoposide, mitoguazone, and vinblastine was used to treat patients with relapsed and refractory malignant lymphoma and Hodgkin's disease. An overall partial response rate of 41% was observed. Although useful responses were seen, the absence of complete remissions is disappointing.

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