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Mitoxantrone: beneficial first- and second-line treatment for breast cancer


Book ID
120859858
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2003
Weight
133 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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Mitoxantrone as a first-line treatment o
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Forty-two Women with measurable or evaluable advanced breast cancer who had received neither prior chemotherapy for advanced disease nor any anthracycline-containing regimen as adjuvant were entered in a phase II study of mitoxantrone (Novantrone| dihydroxyanthracenedione). Patients were aged from 3

First-line combination chemotherapy with
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In this study, 30 evaluable patients with advanced carcinoma of the breast were treated with cyclophosphamide 600 mg/m2 i.v. followed one day later with mitoxantrone (Novantrone; dihydroxyanthracenedione) 16 mg/m2 i.v. Drug treatment was repeated every 3-4 weeks, for a maximum of 12 cycles. The over