Mitoxantrone as first-line chemotherapy
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H. T. Mouridsen; Michael Cornbleet; Robin Stuart-Harris; Ian Smith; Robert Colem
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Article
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1985
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Springer US
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English
β 565 KB
Mitoxantrone (Novantrone| dihydroxyanthracenedione) is a substituted anthraquinone with a spectrum of activity similar to doxorubicin in experimental tumors. One hundred and seventy three patients with advanced breast cancer and no prior cytotoxic therapy for advanced disease entered a phase II stu