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Mitotic degradation of cyclin A is mediated by multiple and novel destruction signals

✍ Scribed by Markus Kaspar; Axel Dienemann; Christine Schulze; Frank Sprenger

Book ID
114318306
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
544 KB
Volume
11
Category
Article
ISSN
0960-9822

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## Abstract XK469 (NSC 697887) is a novel antitumor agent with broad activity against a variety of tumors. Previous studies suggest that XK469 is a topoisomerase IIΞ² poison with functional activity similar to that of 4′‐(9‐acridinylamino) methanesulfon‐m‐anisidide (__m__‐AMSA). The goal of our stud