Mitotic cycles in human cell strains with sex chromosomes aneuploidy
β Scribed by V. I. Kukharenko; K. N. Grinberg; A. M. Kuliev
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 285 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0340-6717
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β¦ Synopsis
A persistence of the embryonic type of mitotic cycle was found in postnatal strains with aneuploidy of sex chromosomes (45,X; 47,XXX; 49,XXXXX; 47,XYY; 49,XXXXY). Life-span and proliferating activity of the strains did not differ from those of diploid postnatal cells.
π SIMILAR VOLUMES
Human leukocyte cultures were irradiated with 200 RX-rays before the addition of phytohemagglutinin (PHA) in the Go-stage and at different times up to 25 h within the first G1-phase of the cell cyle after the addition of PHA. The results of the analysis of chromosomal aberrations show that the frequ