## Abstract Early studies on the duration of mitotic stages and on metaphaseβtoβprophase ratios in a number of normal and neoplastic cells indicated that the process of mitosis becomes altered during the course of oncogenesis. However, the nature of these changes and their effects on each of the mi
Mitotic behavior of a culture of human diploid cells at various stages of transformation by virus SV40
β Scribed by I. A. Alov; M. E. Aspiz; V. N. Blyumkin; V. I. Gavrilov; A. I. Solov'eva
- Publisher
- Springer US
- Year
- 1967
- Tongue
- English
- Weight
- 431 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0007-4888
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A clone of hamster fibroblasts tramformed by SV40 virus (TSVKCL,) induced antibodies in hamsters against new antigenic constituents not present in the untransformed fibroblasts. The antibodies in the immune sera against histocompatibility antigens and those against nuclear T antigen were absorbed. T
## Abstract The proliferative activity of diploid human WIβ38 cells in sparse cultures depends on the extracellular concentration of free (or physiologically available) calcium, and cultivation in a medium having a calcium concentration of 0.1 mM or less gradually, but reversibly, arrest their prol
Primary rat embryo cells were transformed by a tsA mutant (tsA640) of simian virus 40 (SV40). Proliferation of all four independent diploid transformants was suppressed at a nonpermissive temperature (40.3\*C), being accompanied by a marked increase in the fraction of cells with a 4N DNA content (a