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Mitosis-Promoting Factor-Mediated Suppression of a Cloned Delayed Rectifier Potassium Channel Expressed in Xenopus Oocytes

✍ Scribed by Andrea Brüggemann, Walter Stühmer and Luis A. Pardo

Book ID: 123640368
Publisher: National Academy of Sciences
Year: 1997
Tongue: English
Weight: 943 KB
Volume: 94
Category: Article
ISSN: 0027-8424
DOI: 10.2307/41238

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## Abstract We previously showed inhibition of K~ir~2 inward rectifier K^+^ channels expressed in __Xenopus__ oocytes by the mitochondrial agents carbonyl cyanide p‐trifluoromethoxyphenylhydrazone (FCCP) and sodium azide. Mutagenesis studies suggested that FCCP may act via phosphatidylinositol 4,5‐