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Mitomycin C-induced mosaicism in C-band regions of human chromosomes 1, 9, 16, and Y

โœ Scribed by Silvana Simi

Publisher
Springer
Year
1985
Tongue
English
Weight
378 KB
Volume
70
Category
Article
ISSN
0340-6717

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โœฆ Synopsis

In order to test the hypothesis that somatic mosaicism involving C-band polymorphism of human chromosomes 1, 9, 16 may arise from mitotic crossing over, peripheral blood lymphocytes from normal males were treated with mitomycin C, which is known to induce somatic crossing over in lower eukaryotes. Evidence is presented which shows that mitomycin C is able to alter the heterochromatic pattern in human lymphocytes.

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