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Mitomycin C and porfiromycin analogs with substituted ethylamines at position 7

✍ Scribed by Iyengar, Bhashyam S.; Sami, Salah M.; Remers, William A.; Bradner, William T.; Schurig, John E.


Book ID
126909464
Publisher
American Chemical Society
Year
1983
Tongue
English
Weight
647 KB
Volume
26
Category
Article
ISSN
0022-2623

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Synthesis of mitomycin C labeled with mo
✍ Yutaka Kanda; Shiro Akinaga; Masaji Kasai 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 French ⚖ 165 KB

## Abstract A first preparation of mitomycin C specifically labeled with mono‐tritium at the C6‐methyl position is described. The key intermediate in the synthesis, 7,7‐ethylenedioxy‐6‐methylenemitosane (5) was made by treating 7,7‐ethylenedioxy‐6‐phenylselenomitosane (4) with meta‐chloroperbenzoic