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MITOMASTER: a bioinformatics tool for the analysis of mitochondrial DNA sequences

✍ Scribed by Marty C. Brandon; Eduardo Ruiz-Pesini; Dan Mishmar; Vincent Procaccio; Marie T. Lott; Kevin Cuong Nguyen; Syawal Spolim; Upen Patil; Pierre Baldi; Douglas C. Wallace

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
153 KB
Volume
30
Category
Article
ISSN
1059-7794

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✦ Synopsis

We have developed a computer system, MITOMASTER, to make analysis of human mitochondrial DNA (mtDNA) sequences efficient, accurate, and easily available. From imported sequences, the system identifies nucleotide variants, determines the haplogroup, rules out possible pseudogene contamination, identifies novel DNA sequence variants, and evaluates the potential biological significance of each variant. This system should be beneficial for mtDNA analyses of biomedical physicians and investigators, population biologists and forensic scientists. MITOMASTER can be accessed at

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