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Mitogenic stimulation of the host enhances susceptibility to scrapie

โœ Scribed by DICKINSON, A. G.; FRASER, H.; MCCONNELL, IRENE; OUTRAM, G. W.


Book ID
109708753
Publisher
Nature Publishing Group
Year
1978
Tongue
English
Weight
323 KB
Volume
272
Category
Article
ISSN
0028-0836

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## Abstract Spleen cells removed from C57Bl/6J mice bearing a methylcholanthreneโ€induced fibrosarcoma (MCโ€16) demonstrate suppressed responsiveness to phytohemagglutinin (PHA) and bacterial lipopolysaccharide (LPS) induced mitogenesis as compared to nonโ€tumorous mice. A similar depression of PHAโ€in