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Mitochondrial toxicity of iron and the protective role of ferritin on dopaminergic PC12 cell line

โœ Scribed by P. Galvani; M. Colleoni; M. Origgi; A. Santagostino

Book ID
116153009
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
440 KB
Volume
9
Category
Article
ISSN
0887-2333

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## Abstract Alterations in iron levels are likely to influence the biological actions of Mn in PC12 cells, because both metals are transported via the divalent metal transporter 1 (DMT1; also Nramp2 or DCT1). Studies were performed to determine the effect of the iron chelator desferrioxamine (DfO)