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Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae − role of protein kinase A in the mitochondrial targeting of CYP2E1

✍ Scribed by Naresh B. V. Sepuri; Sanjay Yadav; Hindupur K. Anandatheerthavarada; Narayan G. Avadhani

Book ID
111312051
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
908 KB
Volume
274
Category
Article
ISSN
1432-1327

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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYP‐mediated mechanisms underlying age‐dependent differences in susceptibility to toxicity. We evaluated CYP expressi