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Mitochondrial Steve: paternal inheritance of mitochondria in humans

โœ Scribed by Lindell Bromham; Adam Eyre-Walker; Noel H. Smith; John Maynard Smith


Book ID
117388382
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
340 KB
Volume
18
Category
Article
ISSN
0169-5347

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In 2002, paternal inheritance of muscle mitochondrial DNA (mtDNA) was reported in a patient with exercise intolerance and a mitochondrial DNA (mtDNA) mutation restricted to skeletal muscle. To evaluate whether paternal inheritance is a common phenomenon, we studied 10 sporadic patients with skeletal