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Mitochondrial respiratory complex I defects in Fanconi anemia

✍ Scribed by Cappelli, Enrico; Ravera, Silvia; Vaccaro, Daniele; Cuccarolo, Paola; Bartolucci, Martina; Panfoli, Isabella; Dufour, Carlo; Degan, Paolo

Book ID
120988451
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
240 KB
Volume
19
Category
Article
ISSN
1471-4914

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## Abstract Measurements of plating efficiency, accumulation of metaphases and generation times have shown that fibroblast from patients with Fanconi anemia (FA) have decreased probability of completing a further division after successful mitosis. Thus FA cells show decreased growth rates and incre