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Mitochondrial respiratory chain and creatine kinase activities in mdx mouse brain

✍ Scribed by Lisiane Tuon; Clarissa M. Comim; Daine B. Fraga; Giselli Scaini; Gislaine T. Rezin; Bruna R. Baptista; Emilio L. Streck; Mariz Vainzof; João Quevedo


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
268 KB
Volume
41
Category
Article
ISSN
0148-639X

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## Abstract Cyclin‐dependent kinase‐5 (CDK5), a unique CDK family member, is active primarily in the central nervous system (CNS). Previous studies suggest that CDK5 is proapoptotic and contributes to tau hyperphosphorylation and neurodegeneration in Alzheimer's disease. The objective of this study