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Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells

✍ Scribed by Shin-Ichi Inoue; Shinichi Noda; Koutarou Kashima; Kazuto Nakada; Jun-Ichi Hayashi; Hiroyuki Miyoshi


Book ID
113622100
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
702 KB
Volume
584
Category
Article
ISSN
0014-5793

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## Abstract Mobilized stem cells in the peripheral blood (PB) must be efficiently harvested at the appropriate time before autologous PB stem cell (PBSC) transplantation. Enumeration of CD34+ cells in the PB before apheresis predicts the number of PBSCs that can be collected, but the cytometric tec