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Mitochondrial protein phosphorylation: instigator or target of lipotoxicity?

✍ Scribed by Wolfgang F. Graier; Roland Malli; Gerhard M. Kostner

Book ID
116909183
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
377 KB
Volume
20
Category
Article
ISSN
1043-2760

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## Abstract Phospholipid scramblase 3 (PLS3) is a member of the phospholipid scramblase family present in mitochondria. PLS3 plays an important role in regulation of mitochondrial morphology, respiratory function, and apoptotic responses. PLS3 is phosphorylated by PKC‐δ at Thr21 and is the mitochon