## Abstract In estrogen metabolic pathways, the COMT enzyme is related to detoxification. __COMT__ gene polymorphisms have been shown to effect enzyme function. We hypothesized that these polymorphisms may be risk factors for endometrial cancer (EC). DNA samples from 150 cases of EC and healthy con
Mitochondrial polymorphisms as risk factors for endometrial cancer in southwest China
β Scribed by L. XU; Y. HU; B. CHEN; W. TANG; X. HAN; H. YU; C. XIAO
- Book ID
- 109085855
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 84 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1048-891X
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## Abstract ## Objective A caseβcohort study was conducted to investigate associations between occupational exposures and endometrial cancer nested within a large cohort of textile workers in Shanghai, China. ## Methods The study included 176 incident endometrial cancer cases diagnosed from 1989
## Abstract ## BACKGROUND. In estrogen biosynthetic pathways, many enzymes are important for metabolism, detoxification, and bioavailability. Polymorphisms in these genes may have an effect on the enzymes' function. For example, higher expression and activation of biosynthetic enzymes and lower ex