Reduced messenger RNA expression level o
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Kazuyuki Matsushita; Susumu Kobayashi; Masataka Kato; Yasushi Itoh; Kazuaki Okuy
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Article
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1996
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John Wiley and Sons
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French
β 631 KB
p2lCipl was first isolated as one of the cyclin-dependent kinase (Cdk) interacting proteins induced by wild-type p53 gene product, and it appears to play an essential regulatory role in the control of cell proliferation as a potent, tight-binding inhibitor of cyclin-Cdk complex that blocks the G,/S