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Mitochondrial membrane permeabilization by HIV-1 Vpr

✍ Scribed by Aurélien Deniaud; Catherine Brenner; Guido Kroemer


Book ID
116751410
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
328 KB
Volume
4
Category
Article
ISSN
1567-7249

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Vpr, one of the accessory gene products encoded by HIV-1, is a 96-residue protein with a number of functions, including targeting of the viral pre-integration complex to the nucleus and inducing growth arrest of dividing cells. We have characterized by 2D NMR the solution conformations of bioactive