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Mitochondrial localization of cyclooxygenase-2 and calcium-independent phospholipase A2 in human cancer cells: Implication in apoptosis resistance

โœ Scribed by Jun-Yang Liou; Nena Aleksic; Shu-Fen Chen; Tsai-Jung Han; Song-Kun Shyue; Kenneth K. Wu

Book ID
118506077
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
864 KB
Volume
306
Category
Article
ISSN
0014-4827

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โœ Sau-Tung Chu; He-Hsiung Cheng; Chun-Jen Huang; Hong-Chiang Chang; Chao-Chuan Chi ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 363 KB

Melittin, a peptide from bee venom, is thought to be a phospholipase A(2) activator and Ca(2+) influx inducer that can evoke cell death in different cell types. However, the effect of melittin on cytosolic free Ca(2+) concentration ([Ca(2+)](i)) and viability has not been explored in human osteoblas