## Abstract Multiple investigations of the effects of peroxisome proliferator‐activated receptor γ (PPARγ) ligands on colon cancer have produced contradictory results. While some studies demonstrated increased numbers of colonic polyps in Apc^Min/+^ mice treated with various thiazolidinedione (TZD)
Mitochondrial Genome Instability and ROS Enhance Intestinal Tumorigenesis in APCMin/+ Mice
✍ Scribed by Dong Kyun Woo; Paula D. Green; Janine H. Santos; Anthony D. D'Souza; Zenta Walther; W. David Martin; Brooke E. Christian; Navdeep S. Chandel; Gerald S. Shadel
- Book ID
- 116203378
- Publisher
- American Society for Investigative Pathology
- Year
- 2012
- Tongue
- English
- Weight
- 938 KB
- Volume
- 180
- Category
- Article
- ISSN
- 0002-9440
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Clinical evidence suggests that estradiol replacement therapy reduces colon cancer risk in ‘post’menopausal women. In colon epithelial cells, the estrogen receptor β (ERβ) is the predominant ER subtype and is thought to mediate the genomic effect of estrogens. The first aim of this stud
## Abstract Epidemiological and experimental evidence suggests that estrogen replacement therapy reduces the risk of colon cancer in postmenopausal women. Estrogen receptor beta (ERβ) is thought to be the principal mediator of the estrogen effect in the colon. Recent studies by our team suggested p