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Mitochondrial dysfunction in CD47-mediated caspase-independent cell death: ROS production in the absence of cytochrome c and AIF release

✍ Scribed by Gaël Roué; Natacha Bitton; Victor J. Yuste; Thomas Montange; Manuel Rubio; Frédéric Dessauge; Cécile Delettre; Hélène Merle-Béral; Marika Sarfati; Santos A. Susin

Book ID: 117456909
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 288 KB
Volume: 85
Category: Article
ISSN: 0300-9084
DOI: 10.1016/s0300-9084(03)00129-9

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## Abstract We reported previously that low levels of nitric oxide (NO) induced cell death with properties of apoptosis, including chromatin fragmentation and condensation in undifferentiated PC12 pheochromocytoma cells. The present study demonstrates that cytotoxicity of low concentrations of NO i