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Mitochondrial DNA synthesis in cell cycle mutants of saccharomyces cerevisiae

โœ Scribed by Newton, Carol Shaw; Fangman, Walton L.

Book ID
122041476
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
546 KB
Volume
5
Category
Article
ISSN
0092-8674

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Mutations in two genes (cdc8 and cdc21) required for nuclear and mitochondrial DNA synthesis in Saccharomyces cerevisiae result in a 6- to 11-fold increase in the rate of mitotic segregation of petites at the permissive temperature. The defect in DNA replication and the increased rate of petite prod