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Mitochondrial DNA sequences are present inside nuclear DNA in rat tissues and increase with age

✍ Scribed by Pilar Caro; José Gómez; Alessandro Arduini; Mónica González-Sánchez; Miriam González-García; Consuelo Borrás; José Viña; María J. Puertas; Juan Sastre; Gustavo Barja


Book ID
116752083
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
454 KB
Volume
10
Category
Article
ISSN
1567-7249

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The nuclear DNA of normal and tumor mouse and rat tissue was examined for mitochondrial-DNA-like inserts by means of the Southern blot technique. The two probes were 32 P-labeled cloned mitochondrial DNA. Kpn I, which doesn't cut either mitochondrial DNA, was one of the restriction enzymes, while th